CD26 expression on CD4+ T cells in patients with cutaneous leishmaniasis
نویسندگان
چکیده
منابع مشابه
CD164 and FCRL3 are highly expressed on CD4+CD26-T cells in Sézary syndrome patients
Sézary syndrome (SS) cells express cell surface molecules also found on normal activated CD4 T cells. In an effort to find a more specific surface marker for malignant SS cells, a microarray analysis of gene expression was performed. Results showed significantly increased levels of mRNA for CD164, a sialomucin found on human CD34+ hematopoietic stem cells, and FCRL3, a molecule present on a sub...
متن کاملLeishmania-reactive CD4+ and CD8+ T cells associated with cure of human cutaneous leishmaniasis.
Fourteen patients suffering from American cutaneous leishmaniasis were studied. Assays of the lymphocyte proliferative response induced in vitro by Leishmania braziliensis antigens were performed. After 5 days in culture, L. braziliensis-stimulated blast T cells were harvested for CD4+ and CD8+ phenotype analysis. When results before and at the end of therapy were compared, leishmaniasis patien...
متن کاملQuality of life in patients with cutaneous leishmaniasis
Introduction: Cutaneous Leishmaniasis (CL) is characterized by papules, nodules or ulcers that most often leave permanent scars in exposed areas of body. This condition can have a severe effect on the quality of life in these patients. This study aims to examine the quality of life in patients with CL. Methods: This cross-sectional study evaluated 120 patients (52 males and 67 females) betwe...
متن کاملAntimonial treatment failure rate in patients with cutaneous leishmaniasis
Background: Despite advances in diagnosis and treatment, leishmaniasis is now considered a severe public health problem, particularly in developing countries, such as Iran. Leishmaniasis is among the six most important, parasitic diseases of the world affecting 88 countries in almost every continent. The disease is complex with different clinical presentations such as visceral, cutaneous and mu...
متن کاملThe Role of CD4 and CD8 T Cells in Human Cutaneous Leishmaniasis
Leishmaniasis, caused by infection with parasites of the Leishmania genus, affects millions of individuals worldwide. This disease displays distinct clinical manifestations ranging from self-healing skin lesions to severe tissue damage. The control of Leishmania infection is dependent on cellular immune mechanisms, and evidence has shown that CD4 and CD8 T lymphocytes play different roles in th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2008
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.2008.03666.x